Replimune Group, Inc.

500 Unicorn Park

Woburn, MA  01801


August 25, 2020




United States Securities and Exchange Commission

Division of Corporation Finance

Office of Healthcare & Insurance

100 F Street, N.E.

Washington, D.C. 20549-6010




Abby Adams






Replimune Group, Inc. Registration Statement on Form S-3 Filed August 11, 2020
(Registration No. 333-244386)


Dear Ms. Adams:


In accordance with Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the above-referenced Registration Statement (the “Registration Statement”) of Replimune Group, Inc. We respectfully request that the Registration Statement become effective as of 4:05 p.m., Eastern time, on August 26, 2020 or as soon as practicable thereafter.  Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Morgan, Lewis & Bockius LLP, by calling Benjamin J. Stein at +1 (781) 724-4258.


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Very truly yours,




Replimune Group, Inc.





/s/ Jean Franchi



Jean Franchi



Chief Financial Officer



Philip Astley-Sparke, Replimune Group, Inc.


Timothy J. Corbett, Morgan, Lewis & Bockius LLP