Replimune Group, Inc.

18 Commerce Way

Woburn, MA  01801


August 15, 2019




United States Securities and Exchange Commission

Division of Corporation Finance

Office of Healthcare & Insurance

100 F Street, N.E.

Washington, D.C. 20549-6010




Sonia Bednarowski






Replimune Group, Inc. Registration Statement on Form S-3 Filed August 8, 2019 (Registration No. 333-233147)


Dear Ms. Bednarowski:


In accordance with Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the above-referenced Registration Statement (the “Registration Statement”) of Replimune Group, Inc. We respectfully request that the Registration Statement become effective as of 4:05 p.m., Eastern Time, on August 15, 2019 or as soon as practicable thereafter.  Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Morgan, Lewis & Bockius LLP, by calling Benjamin J. Stein at (617) 341-7775.


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Very truly yours,







Replimune Group, Inc.








/s/ Philip Astley-Sparke




Philip Astley-Sparke




Executive Chairman






Robert Coffin, Replimune Group, Inc.


Timothy J. Corbett, Morgan, Lewis & Bockius LLP


[Signature Page to Request for Acceleration of Effectiveness of Registration Statement]