August 8, 2019 Robert Coffin, Ph.D. President and Chief Executive Officer Replimune Group, Inc. 18 Commerce Way Woburn, MA 01801 Re: Replimune Group, Inc. Preliminary Proxy Statement on Schedule 14A Filed July 29, 2019 File No. 001-38596 Dear Dr. Coffin: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Healthcare & Insurance cc: Benjamin J. Stein, Esq.